Immunogenicity and Safety of 23-Valent Pneumococcal Polysaccharide Vaccine in Healthy Volunteers Aged 2 Years and Above

Inclusion Criteria: * 2 years old and above healthy people. * Subject or legal representative who consent and has signed written informed consent. * Subject or legal representative who is able to comply with all study procedures. * Subject who didn't vaccinate pneumococcal vaccines and did't immune with any live vaccine within 14 days and inactivated vaccine within 7 days before vaccination. * Axillary temperature ≤37.0 ℃. Exclusion Criteria: * History of allergy，eclampsia, epilepsy, encephalopathy and mental disease or family disease. * Allergic history after vaccination. * Known allergy to any component of the test vaccine（the test vaccine mainly contains 23 types of pneumococcal polysaccharide and PBS buffer） * Subjects who diagnosis of thrombocytopenia or other history of coagulopathy. * Known immunological impairment or dysfunction. * Subjects who have received whole blood, plasma, and immunoglobulin therapy within one month. * Known severe congenital malformations, developmental disorders; clinically diagnosed serious chronic diseases: down's syndrome, diabetes, sickle cell anemia or neurological disorders, Guillain Barre syndrome. * Known or suspected to suffer from: respiratory system disease，acute infection or chronic disease active period，severe cardiovascular disease, liver and kidney disease, malignant tumor, skin disease,children's mother has HIV infection and other serious and infectious diseases. * In pregnancy or lactation or pregnant women. * Subjects aged 18 years and above whose systolic blood pressure≥160mmHg and diastolic blood pressure≥100mmHg. * Any contraindications that investigators consider related to vaccination.