The primary objective of the study aims to study transition toward schizophrenia in patients with learning disorders, and to compare the risk between patients with specific learning disorders, and patients with complexed learning disorders (by two types: patients with other neuro-developmental disorders including executive function disorders, and patients with anxiety).
As secondary objectives, the study aims to: * argue the clinical predicted markers (neuropsychological) transition toward psychosis. * test the feasibility and the acceptability of a early diagnosis for a potential applicable guidance for different referent centers of learning in French territory. * have a better classification of patients with learning disorders in order to target a prospective primary prevention of risk of psychosis via the questionnaires (AQ of Baron-Cohen: Autism-spectrum quotient auto-questionnaire; Inventory of Beck Anxiety Inventory, auto-questionnaire for panic disorder and general anxiety; Liebowitz Social Anxiety Scale). * improve identification of the early signs and the early emerging psychological diseases intervention management (schizophrenia). * Psychic disability: prevent and reduce non-seeking care and accompaniment situations, and risk of rupture of care. * permitting better care of psychosocial rehabilitation with cognitive evaluation. This study will be conducted in Centre de référence des troubles du langage et des apprentissages, Hôpital Raymond Poincaré, APHP, in France.
Study Type
OBSERVATIONAL
Enrollment
20
Comprehensive assessment of at-risk mental states (CAARMS) will be used.
Autism-spectrum quotient (AQ) auto-questionnaire will be used.
An inventory for measuring clinical anxiety: Beck Anxiety Inventory (BAI); Liebowitz Social Anxiety Scale.
Centre de référence des troubles du langage et des apprentissages, Hôpital Raymond Poincaré
Garches, France
Semi-structured interview
Assessement with Comprehensive Assessment of At-Risk Mental States (CAARMS) during 6 to 90 minutes at the center of Raymond Poincaré hospital. The unique collection during the interview, quotation of each patient will be given from the assessement. There will be 4 groups by the results: CAARMS negative subjects, vulnerable subjects, attenuated psychosis subjects and subjects with brief and limited intermittent psychotic syndrome. The further statistic comparison will be done between the 3 last groups classified with results of CAARMS.
Time frame: At baseline
Autistic screening
Autism-spectrum quotient (AQ) auto-questionnaire will be used to evaluate difficulty in social interaction.
Time frame: At baseline
Anxiety measuring
An inventory for measuring clinical anxiety: Beck Anxiety Inventory
Time frame: At baseline
Social interaction difficulty evaluation
Liebowitz Social Anxiety Scale as questionnaire
Time frame: At baseline
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