Screening of NASH in Oupatients Followed in Various Hospital Specialty Clinics at the University Hospital of Strasbourg

Inclusion Criteria: * age ≥ 18 years * outpatients followed at specialty clinics in HUS and at risk of NAFLD: with at least one metabolic risk factor (overweight, diabetes mellitus, hypertension, hypertriglyceridemia) and/or elevated transaminases and/or liver steatosis on US. * endocrinology cohort : type 2 diabetes patients * infectious disease cohort : HIV positive patients * rheumatology cohort : patients with psoriasis, gout or rheumatoid arthritis * nephrology cohort : patients with chronic kidney disease such as diabetic nephropathy or hypertensive nephropathy, including those receiving hemodialysis. * cardiology cohorts: patients with history of angina, myocardial infarction, stroke or arteritis of lower limbs. * internal medicine cohort: patients with auto immune systemic diseases such as lupus, sclerosis or rheumatoid arthritis. * subjects who have given their informed consent * Subjects affiliated to a social security system Exclusion Criteria: * alcohol consumption \> 30g/d in male or \> 20g/d in female in the past 6 months * history of chronic viral hepatitis * history of liver auto immune disease, genetic hemochromatosis, Wilson disease * biliary disease, bile duct obstruction * drug-induced liver injury * secondary liver cancer or other active cancer * organ graft * use of medications associated with secondary NAFLD (corticosteroids, tamoxifen, amiodarone, methotrexate). * congestive heart failure * AIDS * pregnancy, breastfeeding * no information could be given to the patient (subject faces emergency situation, comprehension difficulties, etc.) * patient under guardianship * patients under judicial protection