Impact of Adding Midzolam to Bupavicaine 0.5% in Regional Spinal Anaesthesia on Maternal Middle Cerebral Artery Velocimetry in Parturients With Severer Preeclampsia

Minia University100 enrolled

Overview

Trial to use GABA mimetic action of midazolam to ameliorate the severe preeclampsia induced neuronal excitotoxicity using middle cerebral artery transcranial doppler resisitive vasculer indices to evaluate . Secondery goal is to study end organ injury

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

100

Conditions

Midazolam in Preeclamptic Patients

Interventions

intrthecl midazolamDRUG

midazolm as as adjuvant in spinal anesthesia

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All parturients with severe preeclampsia for urgent C.S Exclusion Criteria: * Ladies refusal to participate. Refusal to have spinal anesthsia

Locations (1)

Elminia university

Cairo, Egypt

RECRUITING

Outcomes

Primary Outcomes

Measuring Pulsatality index and resistive index of maternal middle cerebral artery

Resistive vasculer indices outcome after intrthecal midazolam injection

Time frame: 2 months

Data from ClinicalTrials.gov

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