The purpose of this research is to study the effects of 1,25(OH)2 D3 (a prescription form of active Vitamin D) on muscle strength and insulin secretion by the pancreas and glucose utilization by skeletal muscle.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
17
0.25micrograms, taken daily for eight weeks, orally
Placebo will be created to mimic the appearance of the study drug
Mayo Clinic
Rochester, Minnesota, United States
Glucose Levels
Blood will be obtained to measure glucose after a glucose tolerance test. The glucose tolerance test involves an overnight fast and then participants will ingest a drink containing 75 grams of glucose with blood obtained over a 120 minute period.
Time frame: Baseline and 8 weeks
Insulin Level
Blood will be obtained to measure insulin level after a glucose tolerance test. The glucose tolerance test involves an overnight fast and then participants will ingest a drink containing 75 grams of glucose with blood obtained over a 120 minute period.
Time frame: Baseline and 8 weeks
C-Peptide Level
Blood will be obtained to measure c-peptide level after a glucose tolerance test. The glucose tolerance test involves an overnight fast and then participants will ingest a drink containing 75 grams of glucose with blood obtained over a 120 minute period.
Time frame: Baseline and 8 weeks
PROMIS 10 Questionnaire
Brief 10 question multiple choice survey
Time frame: 8 weeks
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