Myocardial injury after noncardiac surgery (MINS) is common, silent, and strongly associated with morbi-mortality. There are some evidences in the littérature showing that troponin elevation pre and/or postoperatively and surgical Apgar score are strongly and independently associated with postoperative morbi-mortality. In this cohort study of orthopedic surgery patients (\> 50years), the aim is to determine MINS incidence and to assess wich peri-operative factors are associated with the occurrence of MINS. The final objective is to create a score to better identified the patients with a MINS and a poor outcome.
Study Type
OBSERVATIONAL
Enrollment
1,600
CHRU Brest
Brest, France
CHU Rennes
Rennes, France
RECRUITINGPostoperative MINS incidence
Troponin elevation \> 5ng/l compared to previous measurement OR troponin elevation \> 65 ng/l
Time frame: 3 days after surgery
Number of Participants with cardiac arrest
Cardiac arrest
Time frame: 3 months
Number of Participants with an episode of acute pulmonary oedema
Acute pulmonary oedema
Time frame: 3 months
Number of Participants with coronary angioplasty
Coronary angioplasty
Time frame: 3 months
Number of Participants with myocardial infarction
Myocardial infarction
Time frame: 3 months
Number of Participants with stroke
Stroke
Time frame: 3 months
Number of Participants with transient stroke
Transient stroke
Time frame: 3 months
Mortality rate
Death
Time frame: 3 months
Revised Cardiac Risk Index for Pre-Operative Risk (Lee score)
Minimum value = 0 Minimum value = 0, maximum value = 6, higher scores mean a worse outcome (higher peri operative mortality risk)
Time frame: Inclusion
Metabolic Equivalent of Task (MET)
Minimum value = 1, Maximum value= 10, a low score (MET \<4) is associated with a capacity to do some light intensity activities and is associated with cardiovascular risk.
Time frame: Inclusion
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