Severe aortic valve stenosis is known to affect heart haemodynamics, endothelial function and body inflammation markers. Our aim is to investigate the weather transcatheter aortic valve implantation in patients with severe aortic stenosis affects heart rate variability, inflammation markers and endothelial function.
Study Type
OBSERVATIONAL
Enrollment
50
Measurement of brachial artery diameter change before and after limb ischaemia.
Measurement HRV using high resolution ECG
Measurement of endothelial inflammation markers
UMC Ljubljana
Ljubljana, Slovenia
Change of heart rate variability
Change of heart rate variability (HRV) estimated with digital high resolution ECG recording
Time frame: 3 to 6 months after TAVI
Change of laboratory value of endothelial inflammation markers
Laboratory determined numerical changes in endothelial inflammation markers
Time frame: 3 to 6 months after TAVI
Change of flow-mediated filatation (FMD) of the brachial artery
% flow-mediated dilatation
Time frame: 3 to 6 months after TAVI
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