Use of CO2 Detectors to Help Provide Effective Breaths During Resuscitation of Preterm Newborns

KK Women's and Children's Hospital50 enrolled

Overview

Effective ventilation is the single most vital intervention to improve outcome of resuscitation in the neonatal population. Assessments of effective ventilations are based on clinical parameters, but may be difficult due to inexperienced personnel as well as observer variability. End tidal CO2 detectors (ETCO2) have been shown to improve effective ventilation in manikin model as well as in video recordings of selective infants where obstructive breaths were recognized objectively by means of lack of colour change. This is a trial evaluating the use of a qualitative end tidal CO2 monitor device during mask ventilation in the delivery room. The investigators hypothesize that using a colorimetric carbon dioxide detector during mask ventilation, it could facilitate recognition of obstructed breaths and reduce the duration of bradycardia and desaturations.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Preterm Birth

Interventions

Eligibility

Sex: ALLMax age: 60 MinutesHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Preterm infants 24+0/7 to 32+0/7 weeks who require mask ventilation during resuscitation Exclusion Criteria: 1. Infants with impaired pulmonary circulation (eg. Cardiac arrest, pulmonary atresia, severe pulmonary stenosis 2. Infants with congenital airway anomalies

Outcomes

Primary Outcomes

Bradycardia and Desaturation Duration

Duration of bradycardia (HR\<100beats per minute) + Desaturation (SpO2 readings below recommended target during respective minutes of life after birth

Time frame: This outcome will be obtained immediately after birth when available on pulse oximetry