The study will enroll children and adolescents (0 - 17 years) suspected of having concussion or mild traumatic brain injury (TBI). Samples of urine and saliva will be collected from the patients as well as from corresponding age- and gender-adjusted healthy controls.
The collected samples will be alienated to the Sponsor who will perform biochemical studies to identify and measure from the samples relative level of the brain injury-specific biomarkers.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Enrollment
58
Samples of urine and saliva will be collected from participants using customary sample collection means.
Satakunta Central Hospital
Pori, Finland
Biomarker levels
Quantitative measurement of the novel glycan-based biomarker using a lectin-binding assay
Time frame: 12 months
Biomarker profiles
Characterization of different glycan structures present in the sample by mass spectrometry analysis
Time frame: 12 months
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