Gabapentin preoperative use for evaluation of benefit to reduce pain during and after surgical office-based abortion.
A double-blind placebo controlled trial of gabapentin in the setting of an ambulatory surgical abortion center where patients receive either the routine intravenous sedation, local cervical anesthesia plus 600mg of gabapentin one hour prior to surgery vs. the same regimen plus placebo one hour prior to surgery. Our primary outcome measure will be post-operative validated pain scores using a 11-point visual analog scale (VAS). Secondary measures will include nausea and vomiting during, after and 24 hours after the procedure. A second and third pain assessment using VAS will be made at 30 minutes and at 24 hours postoperatively.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
219
Preoperative treatment with Gabapentin
Preoperative treatment with Placebo
Birth Control Care Center
Las Vegas, Nevada, United States
Pain Score
100mm Visual analog scale (VAS) for level of pain, 1-100, 1=no pain, 100= extreme pain
Time frame: 5 minutes postoperative
Pain Score 24
Pain at 24 hours postoperative on 100mm VAS, 1=no pain, 100=extreme pain
Time frame: 24 hours postop
Nausea
Nausea at 24 hours using 100mm VAS, 1=none, 100=extreme
Time frame: 24 hours postoperative
Vomiting
Vomiting at 24 hrs, 100mm VAS, 1=none, 100=extreme
Time frame: 24 hours postoperative
Pain Score at 30 Minutes Postoperative
100mm Visual analog scale for level of pain, 1-100, 1=no pain, 100= extreme pain
Time frame: 30 minutes postoperative
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