Anastomotic Leak Testing in Gastrectomy

Nanchong Central Hospital148 enrolled

Overview

Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis. However, the reliability, clinical benefits and safety of intraoperative leak testing are controversial. Our aim is to evaluate the effect and safety of intraoperative leak testing, and to compare the surgical complications of patients in intraoperative leak testing group with patients in non-intraoperative leak testing group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

148

Conditions

Anastomotic Leak Gastric Cancer

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. resectable gastric carcinoma according to the eighth edition of the TNM (clinical stages I-III). 2. Eastern Cooperative Oncology Group performance status of 0 or 1. 3. American Society of Anesthesiologists class of I-III. Exclusion Criteria: 1. Patients had distant metastasis. 2. presence of obvious contraindications to surgery (e.g., liver and/or kidney function abnormalities). 3. any participation in another clinical trial within the past 6 months. 4. Previous chemotherapy or radiation therapy for any other malignancies. 5. past history of gastric resection, gastric cancer-related complications, other malignancy diagnosed within the previous 5 years,

Outcomes

Primary Outcomes

Anastomotic leakage

all patients underwent upper gastrointestinal radiography after surgery for detecting the integrity of anastomosis. X-ray to detect the integrity of the anastomosis

Time frame: 2 months

Secondary Outcomes

Postoperative surgical complications

Any surgical complication that occured postoperatively

Time frame: 3 months