Heart Rate Variability in Children and Adolescents With Cystic Fibrosis

Universidad Europea de Madrid19 enrolled

Overview

This study aims to assess the effects of a resistance exercise training program on heart rate variability in a group of children and adolescents with cystic fibrosis. The study design is a randomized controlled trial.

A randomized controlled study will be carried out in children diagnosed with cystic fibrosis aged 6 to 18 years. Individuals will be divided into two groups: control group (CON) and strength training (ST). Heart rate variability will be analyzed using KUBIOS and measured using a Suunto watch, with subjects in lying position without movements or speaking for 5 minutes. Patients in the ST group will complete an individualized guided strength program for 8 weeks (3 sessions of 60 min/week). Training prescription will be individualized and based on the 5 repetition maximum test (60-80%). Upper and lower limbs exercises will be used, including seated bench press, seated lateral row and leg press. Outcome measures will be performed at baseline and after 8 weeks.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Cystic Fibrosis in Children

Interventions

ExerciseOTHER

Resistance exercise program for 8 weeks, 3 times a week, with a 60 min session duration.

Eligibility

Sex: ALLMin age: 6 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of Cystic Fibrosis * Age between 6 and 18 years old * Mild to moderate lung function levels * Signature of the informed consent form by legal guardian and patient. Exclusion Criteria: * Active smoking * Exacerbation in the last 3 months * Presence of gastrostomy * Use of beta-blocker drugs * Diagnosed heart disease * Alterations in the locomotor system

Locations (1)

Escuela de Doctorado e Investigacion, Universidad Europea

Villaviciosa de Odón, Madrid, Spain

Outcomes

Primary Outcomes

Change in the standard deviation of R-R intervals (SDNN) expressed in milliseconds (m/s)

Changes in time-domain SDNN will be measured through heart rate variability assessment using a heart rate band and an Ambit 3 Sport watch. Variables will be collected during a five minute period.