The purpose of this study is determine salivary gland disposition of d-limonene, the primary component in citrus peel and a common dietary supplement. Salivary gland tissue and saliva will be collected to determine concentration of d-limonene and its metabolites in these tissues.
Primary Objective: To determine the bioavailability of Alda-341 in salivary gland tissue. Secondary Objective: To determine the bioavailability of Alda-341 in saliva and blood
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
10
Dietary supplement d-limonene orally administered as a drug.
Stanford University
Stanford, California, United States
Bioavailability of Alda-341 in salivary gland tissue using GCMS
Bio availability of Alda-341 in salivary gland tissue will be measured using gas chromatography mass spectrometry (GCMS). The scale is is 4ng/mL - 8000ng/mL.
Time frame: 2 week
Bioavailability of Alda-341 in saliva and blood
Bio availability of Alda-341 in saliva and blood will be measured using gas chromatography mass spectrometry (GCMS). The scale is is 4ng/mL - 8000ng/mL.
Time frame: 2 week
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