Procyanidin B2 Enriched Cocoa Effects on Mitochondrial Biogenesis

N/ACompletedNCT04301583

Universidad Europea de Madrid38 enrolled

Overview

The purpose of this study is to test how cocoa-rich procyanidin B2 affect the mitochondrial exercise adaptations.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Athletes

Interventions

procyanidin B2 enriched cocoaDIETARY_SUPPLEMENT

Volunteers will intake 5 grams per day of dietary supplement for 10 weeks

Eligibility

Sex: ALLMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Men/Women * Age between 18 and 45 years * Aerobic power of oxygen consumption greater than or equal to 55 mL / kg / min Exclusion Criteria: * Smoke * Any chronic disease * Intake of nutritional or ergogenic supplements * Chronic medication * Cocoa allergy

Locations (1)

Universidad Europea de Madrid

Villaviciosa de Odón, Madrid, Spain

Outcomes

Primary Outcomes

Difference in mitochondrial number

Number of mitochondria in blood cells measured by qPCR using mitochondrial COX1 gene and beta globin as housekeeping nuclear gene

Time frame: 10 weeks

Difference in exercise performance

Maximum oxygen consumption * of incomplete pulmonary gas exchange on VO2 max - Powers - Citado por 318 * determination of cardiorespiratory fitness and training … - Clark - Citado por 180 Maximum oxygen consumption

Time frame: 10 weeks

Data from ClinicalTrials.gov

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