Ultrasound guided erector spinae plain block combined with general anaesthesia versus conventional general anaesthesia in lumbar spine surgery, it's hypothesized that combined regional anaesthesia with general anaesthesia in lumbar spine surgery may reduce the anaesthetic requirements, aid in controlled hypotension and improve the perioperative pain management.
Primary outcomes: • Anaesthetic requirements: based on entropy monitoring(state and response entropy monitoring and the difference as a measure for adequacy of analgesia) and haemodynamic parameters ( heart rate and mean arterial blood pressure) at the following time intervals: before induction, after induction, after giving either ESP block or multimodal analgesia and starting surgical stimulus, at 30 min intervals, at end of anaesthesia, at eye opening. Secondary outcomes: * Stress response measurement based on serum cortisol and blood glucose levels * Controlled hypotensive anaesthesia: various drugs required and doses given * Intraoperative and postoperative analgesia. * Postanaesthesia care unit data concerning recovery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
30
20 ml local anaesthetic are injected bilaterally on each side of the surgical incision underneath the erector spinae muscle where the dorsal rami pass around the bases of the transverse processes.
Ketorolac 0.75 mg/ Kg and paracetamol 10 mg/ Kg intravenously
Alexandria faculty of medicine
Alexandria, Egypt
Anaesthetic requirements:
based on entropy monitoring and haemodynamic parameters.
Time frame: the surgery period
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