VOPITB a New Devices to Determine Peripheral Arterial Stiffness: Validation Study

University of Extremadura120 enrolled

Overview

Our group has developed a device called "Velocidad Onda de Pulso Indice Tobillo Brazo (VOPITB)" . In this device the oscillometric method is used for easily and accurately measure the pulse wave velocity PWV in the arms and legs separately, allowing new arterial stiffness indices to be studied (sum, difference, ratio, baPWV and CAVI). The aim of our study will be to validate the PWV measures by VOPITB with other references devices that measures arterial stiffness. Moreover we will perform a clinical study to assess the clinical utility of VOPITB.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Cardiovascular Risk Factor Cardiovascular Diseases Atherosclerosis of Artery

Interventions

arterial stiffness measurements

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects ≥ 18 years who agree to participate in the study and do not meet any of the exclusion criteria. Exclusion Criteria: * History of CVD (ischaemic heart disease, stroke or peripheral arterial disease) * Atrial fibrillation or other cardiac rhythm disorders * Pacemaker-dependent * Impalpable arterial pulse at site of measurement * Pregnancy * Terminal condition * Age under 18 years

Outcomes

Primary Outcomes

cardio-ankle vascular index (CAVI) validation

We will determine CAVI with VOPITB, as well as its validation against the reference device (VaSera VS-1500) and assess its clinical utility.

Time frame: 8 months