Colorectal Cancer Screening Using Stool DNA-based SDC2 Methylation Test

Inclusion Criteria: * Patient who agreed the clinical trial and signed informed consent * High risk patient for colorectal cancer (family history of colorectal cancer, history of adenomatous polyp excision, inflammatory bowel disease \> 15 years, or history of hereditary colorectal cancer) * Patient who scheduled to receive colonoscopy * Stool \> 20g before bowel preparation for colonoscopy Exclusion Criteria: * No high risk patient under 60 years * History of colorectal cancer * Stool \< 20g or sample after bowel preparation * Diarrhea or liquid stool which cannot be evaluated * Patient who is judged as not suitable for clinical trial including a psychiatric disorder by a physician