The purpose of this study is to compare the taste, and the levels in blood plasma of different tablet formulations of BMS-986165 when taken by healthy adults.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
40
Specified dose on specified days
Specified dose on specified days
PRA Health Sciences - Lenexa
Lenexa, Kansas, United States
Maximum concentration (Cmax) in plasma for BMS-986165
Time frame: Up to 26 days
Area under the plasma concentration-time curve from time 0 to the last quantifiable concentration (AUC(0-T)) in plasma for BMS-986165
Time frame: Up to 26 days
Area under the plasma concentration-time curve extrapolated to infinity (AUC(INF)) in plasma for BMS-986165
Time frame: Up to 26 days
Incidence of Adverse Events (AEs)
Time frame: Up to 26 days
Incidence of Serious Adverse Events (SAEs)
Time frame: Up to 98 days
Incidence of clinically significant changes in physical examination findings
Time frame: Up to 68 days
Incidence of clinically significant changes in vital signs: Weight
Time frame: Up to 68 days
Incidence of clinically significant changes in vital signs: Body temperature
Time frame: Up to 68 days
Incidence of clinically significant changes in vital signs: Respiratory rate
Time frame: Up to 68 days
Incidence of clinically significant changes in vital signs: Blood pressure
Time frame: Up to 68 days
Incidence of clinically significant changes in vital signs: Heart rate
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Time frame: Up to 68 days
Incidence of clinically significant changes in electrocardiogram (ECG) parameters
Time frame: Up to 68 days
Incidence of clinically significant changes in clinical laboratory results: Hematology tests
Time frame: Up to 68 days
Incidence of clinically significant changes in clinical laboratory results: Clinical chemistry tests
Time frame: Up to 68 days
Incidence of clinically significant changes in clinical laboratory results: Urinalysis tests
Time frame: Up to 68 days