Prone Position in Non-Invasive Ventilation and High-Flow Oxygen Therapy

Hospital General Universitario Morales Meseguer100 enrolled

Overview

The aim of this trial is to study the effect of prone position during NIV and HFNC on acute hypoxemic respiratory patients.

Inclusion Criteria: Adult patients with: • ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level) Exclusion Criteria * General NIV or HFNC contraindications * Immediate need for IOT * Prone position intolerance * Patients refusal to participate Interventions: * Prone position for 2-4 hours twice a day, for 3 days (first 3 days since admission to ICU) * Nurse surveilance: at least every 15 minutes Outcomes: * Need for IOT * Effects on the measurements specified above (particularly PaO2/FiO2)

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

100

Conditions

Evaluation of Prone Position Effect During NIV and HFNC on Acute Hypoxemic Respiratory Failure

Interventions

Prone position during non-invasive respiratory supportDEVICE

HFNC and NIV application with patient on prone position

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients with: * ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level) Exclusion Criteria: * General NIV or HFNC contraindications * Immediate need for IOT * Prone position intolerance * Patients refusal to participate

Outcomes

Primary Outcomes

Oro-tracheal entubation

Oro-tracheal entubation avoidance

Time frame: 1 month

Secondary Outcomes

PaO2/FiO2

Effect of prone position on PaO2/FiO2

Time frame: 1 month

Central Contacts

Miguel Guia, MD

CONTACT

00351915774975 miguelguia7@gmail.com

Data from ClinicalTrials.gov

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