PENG Block Combined to Wound Infiltration for Hip Replacement

Campus Bio-Medico University60 enrolled

Overview

This study analyze the effect of Pericapsular Nerve Group (PENG) Block combined to wound infiltration for analgesia after elective hip replacement. Half of participants will receive a PENG Block combined with wound infiltration, while the other half will receive wound infiltration alone.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Postoperative Pain Analgesia Hip Arthropathy Acute Pain Pain Postoperative Complications

Interventions

PENG blockPROCEDURE

After performing spinal anesthesia, PENG block with 20 mL of 0.375 % Ropivacaine will be executed as described by Giron-Arongo et al with a low frequency curvilinear probe. A 22G 80 mm needle (Stimuplex Ultra 360, Braun ) will be used.

Wound InfiltrationPROCEDURE

At the end of operation, the surgeon will perform wound infiltration with 20 mL of 0.375 % Ropivacaine.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Elective hip replacement surgery * ASA physical status score \< 4 Exclusion Criteria: * Contraindications to regional anesthesia * ASA physical status score ≥ 4 * Patient's refusal or inability to sing the informed consent * Pre-operatively therapy with opioids * Allergies to any drug provided by the study protocol

Locations (1)

Università Campus Biomedico

Roma, Italy

Outcomes

Primary Outcomes

Maximum Pain Score

A visual analog pain scale anchored by "no pain" (score of 0) and "pain as bad as it could be" or "worst imaginable pain" (score of 100 \[100-mm scale\]) will be used to evaluate pain during 48 h after surgery

Time frame: 24 hours

Total opioids consumption

Total of Sublingual Sufentanil tablets released

Time frame: 48 hours

Secondary Outcomes

Time to first opioid

Time (hours) from the end of surgery to the first opioid administration

Time frame: 48 hours

Range of hip motion

Degrees of hip flexion

Time frame: 24 hours

Time to ambulation

Time until the patient is able to stand up and walk with or without assistive devices

Time frame: 48 hours

Quadriceps weakness

Presence of weakness of the quadriceps using a scale where 0= no effect; 1 = knee flexion possible but not hip flexion; 2 = absence of knee and hip flexion

Time frame: 48 hours

Incidence of block complications

Any complications or side effects of the blocks, such as local infection, intravascular injection of local anesthetics and immediate systemic toxicity.

Time frame: 48 hours

Opioids side effects

The presence or absence of opioids side effects such as drowsiness, desaturation, nausea and vomiting

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.