Comparative Study of Minimally Invasive Surgical Approaches for Total Hip Arthroplasty

National and Kapodistrian University of Athens90 enrolled

Overview

Total hip arthroplasty is a method of choice for treating advanced osteoarthritis of the hip and one of the most frequent orthopedic procedures. Of all hip surgical approaches described, the tendency for minimally invasive techniques has been dominated over the last few years due to faster patient mobilization, reduced postoperative pain and need for blood transfusion. Two of the most common approaches used for minimally invasive total hip arthroplasty are: AMIS anterior approach and mini-posterior approach, which is a modification of the standard posterior approach. The purpose of this study is the biochemical, imaging and clinical evaluation of the tissue damage caused by the above-mentioned techniques of minimally invasive total hip arthroplasty.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hip Osteoarthritis Hip Arthropathy Minimal Invasive Anterior Approach

Interventions

Mini posterior approach Total Hip ReplacementPROCEDURE

Total hip replacement in patients suffering from hip osteoarthritis using the mini posterior approach

Anterior approach total hip replacement without a traction tablePROCEDURE

Mini Anterior approach total hip replacement in patients suffering from hip osteoarthritis without the aid of a traction table

Anterior approach total hip replacement with a traction tablePROCEDURE

Mini Anterior approach total hip replacement in patients suffering from hip osteoarthritis with the aid of a traction table

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients that sign the Informed consent * Patients aged 18 years and over who are going to undergo primary total hip arthroplasty Exclusion Criteria: I. Active infection II. Previous hip operation in any leg III. Any kind of operation the past 3 months IV. Obesity (BMI, Body Mass Index \>30) V. Autoimmune diseases or myositis of any etiology VI. Active cancer

Outcomes

Primary Outcomes

Tissue damage change

Investigate and quantify at the biochemical level with all available biomarkers the extent of tissue damage caused during a hip arthroplasty between different hip surgical approaches.

Time frame: Change from 6 to 24 and then 48 hours post-surgery

Secondary Outcomes

Imaging

All patients will be subjected to imaging with a hip MRI

Time frame: Day 30 after surgery

Clinical Tests change

All patients will be monitored postoperatively for the prescribed period and data will be recorded.

Time frame: Change to clinical test from Day 2 to day 15 and then day 30 post-surgery