Study of Jaktinib Hydrochloride Tablets in Participants With Idiopathic Pulmonary Fibrosis

Inclusion Criteria: 1. Written informed consent signed;at least 50 years of age;no gender limitation. 2. Diagnosed idiopathic pulmonary fibrosis(see 2018.9 guidance that AST and ERS and JRS and ALAT publish ); 3. FVC%≥45% normal predicted value; 4. DLCO≥30% normal predicted value； 5. FEV1 / FVC ≥0.7 Exclusion Criteria: 1. A plan of lung transplant after into group for one year. 2. In addition of IPF,Other causes cause interstitial lung disease in patients； 3. Patients with bleeding tendency (INR \> 2, PT or APTT \> 1.5 times normal) or cerebral hemorrhage in the past 1 year; 4. Have used anticoagulant drugs within 1 month（Except for low molecular weight heparin）; 5. An alcoholic or drug abuser; 6. Expected survival ≤ one year; 7. Patients who plan to undergo a operation within study period, such as major operations on chest and abdomen; 8. Previous use of a JAK inhibitor for more than 10 days or treatment failure; 9. Suspected allergic to Jaktinib Dihydrochloride Monohydrate , similar drugs (Fedratinib,Ruxolitinib)or their excipients; 10. Patients with malignant tumors in the previous 5 years; 11. Patients with other serious diseases that investigators believe may affect patient safety or compliance; 12. Any significant clinical or laboratory abnormalities that the investigator considers to affect safety assessment, such as: a. uncontrolled diabetes (13.9 tendency \> / L), b. had high blood pressure and antihypertensive drug treatment under two or unable to descend to the ranges (systolic blood pressure \< 160 mmHg, diastolic pressure \< 100 mmHg), c. peripheral neuropathy (NCI - CTC AE v5.0 standard grade 2 or above)； 13. Patients hospitalized for deterioration or acute exacerbation of IPF within 1 month prior to screening; 14. patients who had not fully recovered from surgery within 1 month prior to screening; 15. Participate in clinical trials of other new drugs or medical devices within 3 months before screening; 16. Prednisone \> 15mg/ day or equivalent within 1 month prior to screening; 17. Those who had used pirfenidone, Nintedanib, azathioprine, cyclophosphamide, cyclosporine A or other immunosuppressive drugs within 1 month prior to screening; 18. A history of congestive heart failure, uncontrolled or unstable angina or myocardial infarction, cerebrovascular accident or pulmonary embolism occurred within 6 month prior to screening; 19. Patients with active TB in the 12 months prior to screening; 20. Screening patients with arrhythmia requiring treatment, or with QTcB \>480ms; 21. At the time of screening, there was evidence of severe impairment of organ function : including ALT and AST \> 2.5uln;DBIL and TBIL \> 2.0 ULN;Serum creatinine \> was 1.5 ULN. 22. Evidence of active and uncontrolled viral infections such as HIV, HBV (HBsAg positive, hbv-dna positive or ≥10000 copies /ml), HCV (anti-hcv antibody or hcv-rna positive), or bacterial, viral, parasitic or fungal infections requiring treatment with any clinical symptoms; 23. patients with a history of progressive multifocal leukoencephalopathy in Screening ; 24. Patients with epilepsy or using antipsychotics(Sleep medicine,for diazepam expect) for treatment of mental illness( schizophrenia,depressed,mania,anxiety,and so on) at the time of screening; 25. Women who are planning to become pregnant or who are pregnant or breast-feeding and who are unable to use effective contraception throughout the trial period;Male patients who did not use condoms during administration and within 1 month after the last dose; 26. Subjects who cannot be treated and followed up according to the protocol; 27. Any subject whom the investigator considers inappropriate for this clinical study.