Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease

Inclusion Criteria: * Written Informed Consent has been obtained prior to any study-related procedures taking place * Written documentation has been obtained in accordance with the relevant county and local privacy requirements, where applicable * Male or female * 18 years of age and older prior to the initial visit * Is a new or established wearer of PROSE lenses with optimized lens fit prior to enrollment in the study * Has been diagnosed with Dry Eye Syndrome, SJS, SS, or GVHD * In the opinion of the investigator, the subject has the ability to follow study instructions * In the opinion of the investigator, the subject has the ability to complete all study procedures and visits Exclusion Criteria: * aphakic (i.e., missing their natural lens inside the eye) * Is currently participating in any other type of eye-related clinical or research study * Is pregnant or nursing as reported by the subject * Has a condition or is in a situation which, in the investigator's opinion, may put the subject at significant risk, may confound study outcomes, or may significantly interfere with the subject's participation in the study. * Has a known and self-reported allergy to the following substances: polyethylene glycol, polyvinyl alcohol, triethanolamine, polyquaternium-1, or edetate disodium, which are components of the Tangible Boost and Hydra-PEG systems or care regimen. * Has had previous ocular surgery within the past 12 weeks * Adults unable to consent (including adults unable to read and understand English) * Individuals who are not yet adults (infants, children, teenagers) * Pregnant women * Prisoners * Employees of BostonSight