The Trial of Ewata Balloon Guiding in the Application of Thrombectomy

Inclusion Criteria: 1. Acute ischemic stroke 2. within 8 hours 3. Patients aged 18-80 years (including critical point) 4. NIHSS score 4-30 (including critical points) 5. Pre-onset mRS score \<2 6. Large vessel lesions were detected by head CT, CTA, MRI, MRA, or DSA 7. The patient or his legal guardian voluntarily signs and dates a written informed 8.consent approved by the ethics committee (IBC). Exclusion Criteria: 1. Head CT exclusion criteria (exclusion if any of the following conditions are met) 2. Cerebral hemorrhage 3. Intracranial tumors, except for small meningiomas 4. Large area of early cerebral infarction (low density shadow \>1/3 cerebral hemisphere) Clinical and laboratory exclusion criteria 1. seizure 2. Symptoms of nervous system loss improved rapidly 3. Severe stroke (NIHSS≥31 points) or mild stroke (NIHSS≤3 points) 4. CT examination of the skull was negative, but subarachnoid hemorrhage was not excluded from clinical symptoms 5. A history of intracranial hemorrhage and subarachnoid hemorrhage 6. A history of cranial trauma in the last 3 months 7. A history of cerebral or myocardial infarction in the last 3 months 8. A history of gastrointestinal or urinary tract bleeding in the last 3 weeks 9. A history of major surgery in the last 2 weeks 10. A history of arterial puncture in the last l weeks that was difficult to stop bleeding 11. Patients with severe cardiac, hepatic or renal insufficiency (\>250 mol/L) or severe diabetes mellitus 12. Physical examination revealed evidence of active bleeding or trauma, such as a fracture 13. Oral anticoagulants have been taken, and INR\>1.7 14. Blood glucose \<2.7 mmol/L or \>22.2 mmol/L 15. Systolic blood pressure \>185 mmHg, or diastolic blood pressure \>110 mmHg Pregnancy 16. There is a tendency of severe bleeding or bleeding disease, platelet count ≤80x109 /L 17. Systemic infection without control or local infection of puncture point Hypersensitivity to contrast media