Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation

Mayo Clinic20 enrolled

Overview

Researchers are trying to improve the understanding of systolic function of the heart at the time of liver reperfusion in patients undergoing orthotopic liver transplantation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Liver Transplant Disorder Reperfusion Injury

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age greater than 18 years * Undergoing primary orthotopic liver transplantation Exclusion Criteria: * Redo orthotopic transplantation * Acute or fulminant liver failure * Patient with pre-existing atrial fibrillation or hypertrophic cardiomyopathy * Patients with an abnormal preoperative stress test (EF \<55%, areas of prior infarct, ongoing ischemia)

Locations (1)

Mayo Clinic in Florida

Jacksonville, Florida, United States

Outcomes

Primary Outcomes

Degree of change in cardiac strain

Evaluate the degree of change to cardiac strain using speckle tracking echocardiography

Time frame: Up to 1 hour after graft reperfusion

Secondary Outcomes

Pattern of right and left ventricular strain

Describe the pattern of right and left ventricular strain throughout the course of orthotopic liver transplantion.

Time frame: Up to 5 hours from the time of surgery start

Data from ClinicalTrials.gov

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