The purpose of this study is to test how different types of interventions may affect how someone takes their pre-exposure prophylaxis (PrEP) medication.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
300
Four weekly nurse delivered counseling sessions plus two optional booster sessions. Sessions last approximately 40-50 minutes each. Sessions employ cognitive behavioral (CBT) techniques, motivational interviewing (MI), and psychoeducation.
Participants get daily text messages on their cell phone reminding them to take their PrEP medication.
University of Miami
Miami, Florida, United States
Fenway Health
Boston, Massachusetts, United States
TFV-DP concentrations
Medication adherence as reported by Tenofovir diphosphate (TFV-DP) concentrations measured using dried blood spot (DBS) testing.
Time frame: 3, 6, 9, 12, 15, and 18 months
Wilson Medication Adherence self-report
Medication adherence as reported by the Wilson Medication Adherence self-report. The questionnaire has a total score ranging from 0-40, with a higher score indicating greater adherence.
Time frame: up to 18 months
Retention in PrEP care
The percentage of participant attendance at follow up visits over 18 month study participation
Time frame: 3, 6, 9, 12, 15, and 18 months
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