Knee Steroid Injection and Blood Sugar Signatur

University of Texas Southwestern Medical Center11 enrolled

Overview

A prospective, observational study assessing the relationship between HbA1c level and the post-injection blood glucose signature. Participants will be non-diabetic, pre-diabetic, non-insulin dependent and insulin dependent type 2 diabetic patients who will be receiving a knee steroid injection. All of them will be consented a week prior to the injection, when the CGM sensor will be applied to the back of the upper arm. This will be removed a week after the injection. KOOS survey as well as VAS will be administered. Adverse events (e.g., change in medication or hospitalization) will be monitored throughout the study.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diabetes Knee Osteoarthritis

Interventions

40 mg Triamcinolone acetonideDRUG

Unilateral knee steroid injection

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Patients at the Parkland Outpatient Clinic * Indication for unilateral knee joint steroid injection for the treatment of knee joint osteoarthritis Exclusion Criteria: * Less than 18 years old * HbA1c \> 12.0% * steroid exposure in the 3 months prior to Visit 1 * 3 or more steroid injections in the preceding 12 months * known contraindication to steroid injection (adverse reaction or allergy, active infection, INR \> 3.0) * lack of improvement with prior knee steroid injection * change in diabetic medication regimen in the last 1 month * significant change in diet within the last 1 month * current use of aspirin * allergy to adhesive * planned MRI, XR, or CT during the 2-week study period

Outcomes

Primary Outcomes

Post-injection glucose levels

Blood glucose levels after injection of steroid to the knee

Time frame: 1 week

Secondary Outcomes

Post-injection adverse events

Adverse events after injection of steroid to the knee

Time frame: 1 week

KOOS Knee survey

KOOS Knee survey administered before and after steroid injection to the knee

Time frame: 2 weeks