The aim of this study is to determine the clinical spectrum and natural progression of Cerebral Small Vessel Disease (CSVD) and in a prospective multicenter study, to assess the clinical, genetic and epigenetic features of patients with CSVD, , to find independent imaging markers, and to optimize clinical management.
Study Type
OBSERVATIONAL
Enrollment
3,000
Department of Neurology , First Affiliated Hospital Fujian Medical University
Fuzhou, Fujian, China
RECRUITINGOverall outcomes in patients with cerebral small vessel disease.
record the occurrence of stroke and use modified Rankin Scale (mRS) to measure the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability.
Time frame: From date of enrollment until the date of death from any cause, assessed up to 30 years
the development of the burden of microbleeds in MRI
using MARS scale to evaluate the development of the burden of microbleeds
Time frame: From date of enrollment until the date of death from any cause, assessed up to 30 years
the development of the burden of white matter hypertension in MRI
using Fazakes scale to evaluate the development of the burden of white matter hypertension
Time frame: From date of enrollment until the date of death from any cause, assessed up to 30 years
the development of lacunes in MRI
record the number and location of lacunes
Time frame: From date of enrollment until the date of death from any cause, assessed up to 30 years
the development of enlarged perivascular space in MRI
record the number and location of enlarged perivascular space
Time frame: From date of enrollment until the date of death from any cause, assessed up to 30 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.