Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19)

N/AUnknownNCT04320056

Laval University216 enrolled

Overview

There is a high risk of transmission of COVID-19 to healthcare workers. In a recent cohort, 29% of the patients hospitalized were healthcare workers. Among the WHO's primary strategic objectives for the response to COVID-19, the first was to limit human-to-human transmission, including reducing secondary infections among close contacts and health care workers. Automated oxygen titration, weaning and monitoring (FreeO2 device) may be a solution to reduce the number of interventions of healthcare workers related to oxygen therapy, to reduce complications related to oxygen and to improve monitoring.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

216

Conditions

Coronavirus Pneumonia Oxygen Toxicity

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age\> 18 years old * patients with acute respiratory failure related to suspected community acquired pneumonia (viral and non viral) requiring oxygen therapy \< 6 L/min (or FiO2\< 0.50) (to maintain SpO2 between 90 and 94% SpO2) without criteria for immediate intubation or ICU transfer. * Patients hospital admission \< 72 hours Exclusion Criteria: * shock state, * no SpO2 signal available, * patient agitation, * pH \< 7.30 (if blood gas available) * PaCO2 \> 50 mmHg, (if blood gas available) or chronic hypercapnia history * Non invasive respiratory support (NIV, High flow Nasal Therapy (HFNT)) at study inclusion * Withdrawal of life support or palliation as the goal of care * patients' or next of kin refusal to participate to the study

Outcomes

Primary Outcomes

The number of interventions

The number of interventions required by healthcare workers to manage oxygen therapy (titration, weaning and monitoring) during 4 hours

Time frame: Hour0 to Hour4

Duration of interventions

The number of interventions required by healthcare workers to manage oxygen therapy (titration, weaning and monitoring) during 4 hours

Time frame: Hour0 to Hour24