The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Fermented Protaetia brevitarsis seulensis powder on Alcohol-induced Liver Disease in adults for 8 weeks.
Previous studies have indicated that Fermented Protaetia brevitarsis seulensis powder may have the ability to improve liver function in adults with alcohol-induced liver disease. Therefore, the investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Fermented Protaetia brevitarsis seulensis powder on liver function in adults with alcohol-induced liver disease; the safety of the compound are also evaluate. The Investigators examine gamma-glutamyl transferase, alanine aminotransferase, aspartate aminotransferase, and other metabolic parameters at baseline, as well as after 4 and 8 weeks of intervention. Sixty adults were administered either 4,000 mg of Fermented Protaetia brevitarsis seulensis powder or a placebo each day for 8 weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
30
This group takes Fermented Protaetia brevitarsis seulensis powder for 8 weeks
This group takes placebo for 8 weeks
Pusan National University Yangsan Hospital
Pusan, Ami-dong, South Korea
RECRUITINGConcentration of Gamma-Glutamyl Transpeptidase
Gamma-Glutamyl Transpeptidase
Time frame: 8 weeks
Concentration of Aspartate aminotransferase
Aspartate aminotransferase
Time frame: 8 weeks
Concentration of Alanine aminotransferase
Alanine aminotransferase
Time frame: 8 weeks
Fatigue Severity Scale
Fatigue Severity Scale, minimum\~maximum values (1\~7), higher scores mean a worse outcome.
Time frame: 8 weeks
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