The project was undertaking by Qilu Hospital of Shandong University in China. The objective is to find out if there is a connection between vitamin D level and the efficacy of dexamethasone for the treatment of adults with newly-diagnosed primary immune thrombocytopenia (ITP).
The investigators anticipate to undertaking a prospective, observational,non-randomized control trial of 60 ITP adult patients. Dexamethasone (given orally at a dose of 40 mg per day for 4 days, two-cycles with an interval of 10 days) will be used in the target patients. Vitamin D level will be detected before the utilization of treatment measures. Depend on the vitamin D level, the patients will be divided into 2 groups(higher vitamin D level group and lower vitamin D level group).Platelet count, bleeding and other symptoms were evaluated before and after treatment.
Study Type
OBSERVATIONAL
Enrollment
60
HD-DXM (orally at 40 mg daily for 4d )
Sustained response to ITP treatments
Percentage of patients maintaining PLT count over 30\*10\^9/L without bleeding
Time frame: 3 months after treatment started
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.