Clinical Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-389

Inclusion Criteria: 1. Healthy adults over the age of 19 years and under the age of 65 years at the time of screening 2. Subject who had 17.5kg/m² ≤ Body Mass Index (BMI) \< 30.5kg/m² and a total body weight of males ≥ 55 kg and females ≥ 45 kg \# BMI=Weight(kg) / Height(m)² 3. Subject without congenital/chronic diseases and without abnormal symptoms or diagnosis based on a medical examination within the last 3 years 4. Subject who were deemed to be appropriate as study subjects in accordance with the screening results (laboratory tests, vital signs, ECG etc.) 5. Subject who signed an informed consent form approved by the Institutional Review Board(IRB) of Chonbuk National University Hospital and decided to participate in the study after being fully informed of the study prior to participation, including the objective, content and characteristics of the investigational drug 6. Subject who consents to the use of reliable contraception during the clinical trial and not to donate his sperm during the study period and until 1 month after the last administration of investigational product 7. Subject with the ability and willingness to participate during the study period Exclusion Criteria: 1. Subjects with a medical evidence or a history (excluding a dental history of periodontal surgery, impacted wisdom teeth removal, etc.) of clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, urinary, cardiovascular, hepatic, psychiatric, neurologic or immune disease 2. Subjects with a medical history of gastrointestinal disease (e.g., gullet disease such as esophageal achalasia and esophagostenosis and Crohn's disease) or operations (excluding simple appendectomy, herniotomy or tooth extraction) that may affect drug absorption 3. Subjects with the following laboratory test result: ☞ ALT or AST \> 2x the upper limit of the normal range 4. History of regular alcohol consumption exceeding 210 g/week within 6 months prior to screening (1 drink (250 mL) of beer (5%) = 10 g; 1 drink (50 mL) of hard liquor (20%) = 8 g; 1 drink (125 mL) of wine (12%) = 12 g) 5. Subjects who smoked more than 20 cigarettes per day within 6 months prior to screening 6. Subjects who had been administered investigational product(s) from other clinical study or bioequivalence study within 6 months prior to the first dose of this study 7. Following vital signs at screening ☞ Sitting systolic blood pressure ≥160 mmHg or \<90 mmHg and/or a sitting diastolic blood pressure ≥100 mmHg or \<50 mmHg at screening 8. Subjects with a medical history of significant alcohol or drug abuse within one year prior to the screening 9. Subjects who had taken any drug(s) known as a strong inducer(s) or inhibitor(s) of drug-metabolizing enzymes within 30 days prior to the first dose of investigational product(s) 10. Subjects who had taken prescription or nonprescription drugs within 10 days prior to the first dose of investigational product(s) 11. Subjects who donated whole blood within 2 months or blood components within 1 month prior to the first dose of the investigational product(s) 12. Subjects with a severe acute/chronic physical and mental conditions that can increase risk or interfere with the interpretation of the results of test 13. Subjects who had Type 1 diabetes or diabetic ketoacidosis 14. Subjects with known hypersensitivity to the drug or the drug ingredient, such as anaphylactic reactions or angioedema 15. Subject had renal impairment(eGFR \< 60 mL/min/1.73 m²) 16. Subject had genetic dysfunctions like galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption 17. Subject who is a pregnant or nursing woman 18. Subject had heart failure(NYHA class IV) 19. Subjects who were deemed inappropriate to participate in the study by the investigator