Influence of Intra-Canal Cryotherapy on Post-Endodontic Pain and Interleukin-6 Expression Using Different Irrigation Protocols: A Randomized Clinical Trial

Suez Canal University48 enrolled

Overview

the study was to evaluate the effect of intra-canal cryotherapy on post-endodontic pain and interleukin-6 expression in teeth with symptomatic apical periodontitis using different irrigation protocols.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Symptomatic Periapical Periodontitis

Interventions

CryotherapyOTHER

cold application

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Anterior or premolar single canal in single rooted teeth. * Patients aged 20 to 50 years. Exclusion Criteria: * Patients under anti-inflammatory medication, immune-suppressive chemotherapy or any antibiotic medication for the last 2 months. * Pregnant or lactating females. * Teeth with endo-perio lesions.

Locations (1)

Ahmed

Port Said, Egypt

Outcomes

Primary Outcomes

PAIN

post-operative pain is measured by using visual analogue scale (VAS) The modified VAS will include a 10 cm straight horizontal line numbered at each centimeter with following criteria: (0) for no pain, (1-3) for mild pain, (4-6) for moderate pain, (7-9) for severe tolerable pain and (10) for severe intolerable pain

Time frame: one week

Data from ClinicalTrials.gov

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