Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips

Inclusion Criteria: * Patients with class IV of Cawood and Howell classification in the anterior maxilla. * Males and females 18-50 years of age. * Patients with adequate oral hygiene. * Patients with healed sites for at least 6 months after tooth extraction. * Patients with an inter-arch distance of at least 6 mm. * Compliance with all requirements in the study and signing the informed consent. Exclusion Criteria: * Patients with diseases of the immune system or systemic disease affecting bone healing * Patients who are chronic users of medications known to affect the periodontal status. * Patients with history of intravenous and/or oral bisphosphonate use. * Pathologic lesions or acute infection in the area of defect. * Patients who are pregnant or lactating mothers. * Heavy smokers who smoke more than 10 cigarettes a day. * Patients with poor oral hygiene that are not amenable to motivation and improvement. * Patients with history of irradiation of the head and neck region. * Vulnerable patients.