Biological treatments (BT) are commonly prescribed to treat chronic inflammatory diseases in children. Paradoxical reactions during treatment with a biological agent can be defined as the appearance or exacerbation of a pathological condition that usually responds to this class of drug while treating a patient for another condition. Limited data are available in children treated by BT on cutaneous paradoxical reactions, or any other cutaneous adverse events occurring during treatment. On the contrary, dermatologists tend to see and manage increasing numbers of cutaneous adverse events, including paradoxical reactions. The aim of this project is to describe the incidence of cutaneous adverse events, including cutaneous paradoxical reactions, occurring in the pediatric population, during a treatment by BT given for a chronic inflammatory disease.
Study Type
OBSERVATIONAL
Enrollment
20
Dermatological consultation will be done on every children treated by biotherapy for chronic inflammatory disease in the Amiens hospital.
CHU Amiens
Amiens, France
Variation of the incidence of cutaneous adverse events under biological therapy
Determine the variation of the incidence of any skin manifestation under biological therapy, including Paradoxical Reaction (psoriasis, eczema, hidradenitis suppurativa …), non-paradoxical inflammatory reaction, infection, neoplasia, hair and nail manifestation, xerosis.
Time frame: up to 8 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.