The purpose of this open label,single arm,phase Ⅱ clinical trail is to determine the safety and efficacy of Chidamide combination with lenalidomide for relapsed or refractory peripheral T-cell lymphoma.
Histone deacetylase(HDAC) inhibitor has been used in relapsed or refractory peripheral T-cell lymphoma.There are no international studies of Chidamide combination with lenalidomide for relapsed or refractory peripheral T-cell lymphoma. Therefore, this study intends to select the oral HDAC inhibitor Chidamide combined with lenalidomide for relapsed or refractory peripheral T-cell lymphoma, and explore its efficacy and safety.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
44
All patients enrolled in the study will accept Chidamide combination with lenalidomide regimen.
Guangdong General Hospital
Guangzhou, Guangdong, China
RECRUITINGORR
Overall Response Rate
Time frame: 4-years
PFS
Progression Free Survival
Time frame: 4-years
DOR
Duration of Overall Response
Time frame: 4-years
OS
Overall Survival
Time frame: 4-years
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