Integration of Mental Health in HIV Clinic to Increase the Success of ARV Treatment in PLWHA in Hospitals

Ina-Respond200 enrolled

Overview

Integration of mental health in HIV clinics is needed in order to accelerate fast track 90-90-90 for controlling HIV. Symptoms of depression are sometimes difficult to recognize. In people living with HIV (PLWHA), depression that fails to be recognized and uncontrolled increases the risk of unsuccessful antiretroviral treatment and mortality. The main purpose of this study is to estimate the proportion of depressive disorders in people living with HIV. The study included adult HIV patients aged ≥18 years, both men and women, who had received ARV treatment for at least six months, with no history of being diagnosed with depression.

This study was a cross-sectional, non-intervention and multicenter in adults with HIV-AIDS (PLWHA) who were treated at a hospital who had received ARV treatment for at least six months, without a history of being diagnosed with depression. Patients from HIV outpatient clinics in each research hospital were briefed on the study and offered to participate. Furthermore, based on the assessment of inclusion and exclusion criteria, PLWHA who meet the requirements were recruited and data were collected. Sociodemographic data, HIV risk factors, risk behaviors, clinical characteristics such as duration of HIV, family history of mental illness, AIDS-related illnesses, other serious non-AIDS-related illnesses, treatment (antiretroviral (ARV) and non-ARV) and history ARV treatment response (HIV and CD4 viral load) were collected from each participant. In addition, a rapid screening for depressive disorders was carried out using the Patient Health Questionnaire-9 (PHQ-9) which was translated and validated in Indonesian. The PHQ-9 questionnaire was filled in by the patient with the assistance of health personnel. The total PHQ-9 questionnaire score were added up and the severity of depression associated with the score was reported to the patient's physician for further management.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

HIV/AIDS Depression

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Adults aged ≥18 years. 2. HIV positive based on diagnosis standards of care in research hospitals. 3. Have received ARV treatment for at least six months. 4. Without a history of being diagnosed with a depressive disorder beforehand. 5. Has been given an explanation before the research and give approval after the explanation. Exclusion Criteria: 1. Being pregnant / nursing. 2. Currently undergoing a period of detention. 3. Being seriously ill (according to the doctor's justification at the hospital).

Locations (4)

Site 600 : Adam Malik Hospital

Medan, North Sumatra, Indonesia

Site 650: Budi Kemuliaan Hospital

Batam, Riau Islands, Indonesia

Site 630: M. Ansari Saleh Hospital

Banjarmasin, South Kalimantan, Indonesia

Site 640: St. Carolus Hospital

Jakarta, Indonesia

Outcomes

Primary Outcomes

Proportion of depressive disorders in PLWHA in hospitals.

Number in percentage for Proportion of depressive disorders in PLWHA in hospitals.

Time frame: [Time Frame: 3 months] [No Safety Issue]

Secondary Outcomes

Distribution of the severity of depressive disorders in PLWHA

Distribution of the severity of depressive disorders in PLWHA catagorized into minimal, mild, moderate, moderate-severe and severe

Time frame: [Time Frame: 3 months] [No Safety Issue]

The correlation of depression with various factors.

The correlation of depression with various factors: the Risk behavior in the past 30 days, socio-demographic, clinical characteristic and ARV response history.

Time frame: [Time Frame: 3 months] [No Safety Issue]