To determine the diagnostic yield of a 30-day smartphone electrocardiogram recording compared to 24-hour Holter monitor for detecting occult paroxysmal atrial fibrillation in patients with a recent ischemic stroke or transient ischemic attack of undetermined etiology after completion of a standard clinical stroke work-up.
Study outcomes Primary: Detection of one or more episodes of atrial fibrillation or atrial flutter ≥30 seconds as assessed at the 30 day follow-up. Secondary: 1. Proportion of patients prescribed oral anticoagulation, as assess at the 30-day follow up. 2. Patient adherence with 30-day smartphone ECG monitoring, and percentage of patients using the monitor \>75% of the target in 30-day period 3. Time to first detection of AF within 30 days (days) 4. One year rate of recurrent ischemic stroke or transient ischemic attack, death, hemorrhagic stroke, major adverse bleeding events, detection of AF outside the study protocol. Exploratory: To explore the feasibility and cost effectiveness of 30-day smartphone ECG recording for detecting occult paroxysmal atrial fibrillation
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
236
Patients who are randomised to the 30-day smartphone ECG monitoring will be contacted within one month from randomisation. Patients will be taught on how to use the smartphone ECG monitoring. Patients are required to monitor their ECG 3 times a day for 30 days. Patients will be contacted during the monitoring period to assess for compliance and to ensure that the recording is done correctly.
SarawakHC
Kuching, Sarawak, Malaysia
Atrial Fibrillation after 30 days
Detection of one or more episodes of atrial fibrillation or atrial flutter ≥30 seconds as assessed at the 30 day follow-up. This will be reported as number of patient detected to have atrial fibrillation after 30 days.
Time frame: 30 days
Proportion of patients prescribed with oral anticoagulation, a assess at the 30-day follow-up
Proportion of patients prescribed with oral anticoagulation, a assess at the 30-day follow-up
Time frame: 30 days
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