This clinical study evaluates risk and protective factor to develop psychopathology in transitional age youth. 300 patients will be recruited at the age of 17 years old and assessed at baseline and 2 years later.
Emerging adults are a particularly at-risk population in mental health. Transitional age youth have specific needs, not currently covered between child and adolescent mental health services (CAMHS) and adult mental health services (AMHS), mainly because of existing barriers. Movements from one to the other must be planned to achieve optimal patient care. Our project aims to identify clinical dimensional characteristics contributing to the development of psychopathology during the transition period. Continuities, discontinuities and resilience factors will be explored. The final purpose is to develop a non-stigmatizing approach to reduce rejection from youths in psychopathological suffering and increase social inclusion. The transversal and trans-diagnostic approach consists of a dimensional evaluation: 300 youth at the age of 17 will be included in a cohort of in-patients, out-patients and control group. Participants will be assessed at baseline and 2 years later. The primary outcome is based on Health of the Nation Outcome Scale for Children and Adolescents, measuring mental health care need, and WHO Quality of Life assessment. The secondary outcomes include the assessment of dimensions representing risk or protective factors to develop psychopathology and evolution of mental health status during transition age. Baseline evaluation consists in internalizing/externalizing symptoms, impulsivity/compulsivity, emotion regulation, cognitive functioning, social and family functioning, developmental, medical and trauma history. At follow-up, mental health pathways and transition results will be described.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
252
First assessment at baseline (T0) - 17 y.o. Follow-up 2 years later (T1) - 19 y.o.
Brugmann University Hospital
Brussels, Belgium
Hôpital Universitaire Des Enfants Reine Fabiola
Brussels, Belgium
Service santé mentale à l'ULB
Brussels, Belgium
Erasme University Hospital
Brussels, Belgium
Change from Baseline self-rated mental health status (need for care) at 2 years
Measured at baseline (T0) and follow-up (T1) with the Health of the Nation Outcome Scale for Children and Adolescents (HoNOSCA).
Time frame: Change from Baseline HoNOSCA before transition at 17 y.o. to after transition at 19 y.o.
Change from Baseline self-rated measure of quality of life at 2 years
Measured at baseline (T0) and follow-up (T1) with the Quality of life assessed by World Health Organisation Quality of Life Assessment (WHO-QoL-BREF)
Time frame: Change from Baseline WHO-QoL before transition at 17 y.o. to after transition at 19 y.o
Self-rated measure of traumatic life events
Measured with Childhood Trauma Questionnaire (CTQ)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of family functioning
Measured with Family Assessment Device (FAD)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure to quantify the risk of developing psychiatric disorders
Measured with General Health Questionnaire (GHQ-12)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of internalising and externalising symptoms
Measured with Youth Self Report 11-18 (YSR)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of impulsivity and compulsivity
Measured with Barratt Impulsiveness Scale (BIS-11)
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Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of depressivity
Measured with Beck Depression Inventory-II (BDI-II)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of suicidal risk
Measured with Beck Scale of Suicide Ideation (BSS)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of emotional regulation
Measured with Emotion Regulation Questionnaire for Children and Adolescents (ERQ-CA)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of interpersonal relationships social adaptation
Measured with Social Adaptation Self-evaluation Scale (SASS)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of cognitive insight
Measured with Beck Cognitive Insight Scale (BCIS)
Time frame: Before transition at 17 y.o. (T0)
Cognitive assessment - IQ
Measured with Wechsler Adult Intelligence Scale (WAIS-IV)
Time frame: Before transition at 17 y.o. (T0)
Executive functions assessment - alertness, divided attention, flexibility and working memory
Measured with Test of Attentional Performance (TAP)
Time frame: Before transition at 17 y.o. (T0)
Executive functions assessment - cognitive inhibition
Measured with STROOP Task
Time frame: Before transition at 17 y.o. (T0)
Executive functions assessment - planning task
Measured with Tower of London Test (TOL)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of executive functions
Measured with Behavior Rating Inventory of Executive Function - Self report (BRIEF-SR)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of transition readiness and appropriateness
Measured with Transition Readiness and Appropriateness Mesure (TRAM)
Time frame: Before transition at 17 y.o. (T0)
Self-rated measure of therapeutic alliance
Measured with Helping Alliance Questionnaire (HAQ)
Time frame: After transition at 19 y.o. (T1)
Self-rated measure of transition related outcomes
Measured with Transition Related Outcomes Mesure (TROM)
Time frame: After transition at 19 y.o. (T1)