IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls

Mai Nasser Abd Elmohsen37 enrolled

Overview

Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also been studied. In our study we aim at establishing a quantitative relationship between preoperative ocular biometrics and postoperative intraocular pressure change and comparing this relationship in glaucomatous and non-glaucomatous eyes.

All patients will have the anterior chamber angle assessed by indentation gonioscopy preoperatively. Anterior Chamber Depth \& lens thickness will be measured by Optical Biometry (lenstar 900) as well as measurement of the angle \& lens vault using the Ultrasound Biomicrosopy (UBM) before and 1 month after cataract surgery. IOP will be measured pre- \& postoperatively on day 7 and 30. Possible Risk (s): Risks of surgery(hemorrhage, endophthalmitis), Risks for investigations: minimal risk of infection To minimize the risk of infection: adherence to pre-\& intraoperative infection-control measures, postoperative UBM is to be done at 1 month.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Glaucoma Cataract

Interventions

phacoemulsification and Intraocular lens implantationPROCEDURE

Standartd surgical procedure with small incision to remove catarct using ultrasound waves. it can be done by topica, local or general anaesthesia acoording to patients general fitness and preference.

Ultrasound Biomicrosopy (UBM)DIAGNOSTIC_TEST

A diagnostic test using ultrasound waves to evaluate the anterior chamber depth, angle and lens vault.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 40-70 years. * Glaucomtous and nonglaucomatous participants with visually significant cataracts. * Best-corrected visual acuity (BCVA) equal to or worse than 6/12. * patients candidates for standard cataract surgeries without adjunctive procedure (e.g., pupil stretching or iris hooks). Exclusion Criteria: * Major intraoperative or postoperative complications from cataract surgery * Peripheral anterior synechiae (PAS) detected by indentation gonioscopy. * Uveitis, severe retinal diseases, or congenital Anomalies. * History of ocular trauma or any intraocular Surgery. ocular trauma or any intraocular Surgery

Locations (1)

Faculty of medicine, Cairo university

Cairo, Egypt

Outcomes

Primary Outcomes

Intraocular pressure change

intraocular pressure measurement by Goldman's applanation tonometr

Time frame: 4 weeks

ocular bio-metrics change

anterior chamber angle angle opening distance and anterior chamber depth change

Time frame: 4 weeks

Secondary Outcomes

Phacoemulsification as treatment to glaucoma

intraocular pressure decrease after surgery in glaucoma patients

Time frame: 4 weeks

Data from ClinicalTrials.gov

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