This study aims to assess the effect of stevia extract on postprandial glucose and insulin levels in overweight and obese adults when compared to sugar and water.
The study is a three-arm crossover trial involving participants attending the Lab on 3 different occasions (separated by 3-5 day washout period), where they will be administered water, sugar solution (65g), water and stevia extract (5g) solution. The solution will be followed by a consumption of a fixed meal (after 30 minutes). Breakfast will be standardised. Capillary blood glucose will be collected every 30 min until 2 hours post meal. Venous blood samples will be collected before the intake of the solution and at 2 hours after meal intake.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Participants will receive a solution of stevia before being administered a fixed meal (lunch). Glucose and insulin levels, and Visual analogue scale data will be collected.
School of Health sciences, Liverpool Hope University
Liverpool, United Kingdom
Postprandial glucose levels
Change in glucose levels two hours after the administration of a fixed meal
Time frame: Capillary blood glucose will be measured two hours after the administration of a fixed meal.
Postprandial insulin levels
Change in postprandial insulin levels two hours after the administration of a fixed meal
Time frame: Postprandial insulin levels will be measured two hours of the administration of a fixed meal
Area under the curve (AUC) for glucose
Changes in AUC for glucose throughout the intervention
Time frame: Capillary blood glucose levels will be collected 6 times on each visit before the intake of the solution until 2 hours post lunch
Subjective feelings of satiety
Visual analogue scales
Time frame: VAS will be collected 6 times on each visit before the intake of the solution until 2 hours post lunch.
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