Clinical Study of Genakumab for Injection in Chinese Healthy Volunteers

Inclusion Criteria: * 18 years ≤ age ≤50 years, and in good health; * 40kg ≤ weight ≤100kg , and body mass index is within the range of 18 - 28 kg/m\^2 (including 18 kg/m\^2 and 28 kg/m\^2); * No parental scheme from the screening period to 6 months after the study period. Exclusion Criteria: * Participants have abnormal physical and auxiliary examination results with clinical significance; * History of cardiovascular, liver, kidney, digestive, blood, nervous system and allergic diseases, mental and metabolic disorders, acute or chronic bronchospastic disease; * Smoking more than 5 cigarettes per day; * Participants who use any prescription drugs within 4 weeks prior dosing, or over-the-counter medication within 2 weeks prior to dosing. Participants who receive treatment of any biologics within three months prior to dosing. Participants who receive (attenuated) live vaccines within six months prior to dosing; * Participation in any clinical investigation within 3 months prior to dosing; * Donation or loss of 400 mL or more of blood within 3 months prior to dosing; donation or loss of 200 mL or more of blood within 4 weeks prior to dosing; or donation of component blood within 2 weeks prior to dosing; * Tuberculosis symptoms, contact with patients with suspected tuberculosis symptoms * Positive results in Hepatitis B surface antigen (HBsAg), Hepatitis C antibody, Syphilis antibody or HIV antibody; * Clinically significant acute infection within 2 weeks prior to dosing; * Current or previous drug or alcohol abuse; * Other conditions in which the investigator preclude enrollment into the study.