Safety and Effectiveness of Low-flow ECMO Driving by CVVH Machine in Severe NCP

Inclusion Criteria: * 1\. NCP with severe acute respiratory distress syndrome with ratio of partial pressure of arterial oxygen over fraction of inspired oxygen (PaO2:FiO2)\<150 and PEEP \>10cmH2O * 2\. Driving pressure\> 20cmH2O * 3\. RR\>30bpm * 4.PaCO2\>55cmH2O and/or PH\>7.3 Exclusion Criteria: * 1\. poor venous vascular condition and unavaible for central venous catheter placement