This study aims to demonstrate the noninferiority of DWP14012 to Lansoprazole 15 mg in the maintenance effect of treatment and confirm the safety of DWP14012 in patients with healed erosive esophagitis confirmed on EGD after medication treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
406
DWP14012 20 mg, tablet, orally, once daily for up to 24 weeks
DWP14012 20 mg placebo-matching tablet, orally, once daily for up to 24 weeks
Lansoprazole 15 mg capsule, orally, once daily for up to 24 weeks
The Catholic University of Korea, Yeouido ST. Mary's Hospital
Seoul, South Korea
RECRUITINGProportion (%) of subjects with remission maintained on esophagogastroduodenoscopy by Week 24
Time frame: at 24 week
Proportion (%) of subjects with remission maintained on esophagogastroduodenoscopy by Week 12
Time frame: at 12 week
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Lansoprazole 15 mg Placebo capsule, orally, once daily for up to 24 weeks