The purpose of this research is to see if the DPP4 inhibitor linagliptin, an oral medication commonly used to treat type 2 diabetes,can help with diabetes control and reduce the severity of the COVID-19 infection
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
5 mg Linagliptin administered by mouth once daily
Standard of care insulin regimen as per hospital protocol
University of Miami
Miami, Florida, United States
Changes in Glucose Llevels
Change in glucose control will be assessed via glucose levels obtained from blood serum samples
Time frame: Baseline, up to 2 weeks
Changes in SpO2 levels
changes in SpO2 will be measured with a Pulseimetry, an indirect, non-invasive method
Time frame: Baseline, up to 2 weeks
Changes in Interleukin 6 (IL6)
Changes in IL 6 will be assessed from blood serum samples
Time frame: Baseline, up to 2 weeks
Changes in chest structures
Changes in Chest radiography (X-ray)
Time frame: Baseline, up to 2 weeks
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