Glaucoma After Congenital Cataract Surgery

N/AUnknownNCT04342052

Sun Yat-sen University351 enrolled

Overview

To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.

A prospective longitudinal cohort study of pediatric patients who underwent surgery for congenital/infantile cataracts between January 2011 and December 2025 was performed.

Study Type

OBSERVATIONAL

Enrollment

351

Conditions

Glaucoma Congenital Cataract

Eligibility

Sex: ALLMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * a diagnosis of bilateral congenital cataracts, the etiologies include congenital idiopathic cataract and congenital cataract associated with a systemic syndrome or ocular anomalies; * cataract surgery performed in ZOC; * age at cataract removal younger than 16 years; Exclusion Criteria: * the preoperative IOP was above 21 mm Hg; * family history of glaucoma; * signs of preoperative glaucoma were present, such as corneal clouding, corneal enlargement, excessive cup-disc ratio and myopic shift; * ocular trauma history; * previous surgery intervention and * they were noncompliant with our follow-up protocol to monitor the occurrence of glaucoma and glaucoma suspect.

Locations (1)

Zhongshan Ophthalmic Center, Sun Yat-sen Univerisity

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

the incidence of glaucoma after congenital cataract surgery

A Kaplan-Meier analysis was used

Time frame: baseline

Secondary Outcomes

Risk factors of glaucoma after congenital cataract surgery

Piecewise exponential survival models with mixed effects (PEWSMME) were used.(variables including demographic characters, surgery categories, clinical history, length of follow up).

Time frame: baseline

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.