Intra-operative PET-CT: a Novel Approach to Determine Excision Margins in Lumpectomy Breast Cancer.

Inclusion Criteria: * • female and 18 years of age or older * diagnosed with an early-stage (T1 or T2, and N0 or N1; according to the TNM-classification) invasive breast cancer * eligible for breast conserving surgery Exclusion Criteria: * • Pregnancy or lactation * Diabetes * Multifocal tumor disease * Diagnosis of inflammatory breast cancer * Appointment at the nuclear medicine department for 18F-FDG administration would result in a unacceptable delay of surgery * Subject has had exposure to ionizing radiation of more than 1 mSv in other research studies within the last 12 months * Subject has recently (\<60 days) or is simultaneously participating in another clinical trial.