Some patients infected by covid-19 develop skin manifestations. These manifestations are still not well known and there pathophysiology remain unclear. Among them, acral manifestation resembling to chilblains appears frequent and quite specific. The aim of this project is to better characterize the cutaneous manifestations occurring during Covid-19 infection with a special focus on chilblains. These acral manifestation could be due to a direct viral effect, but also to microthrombosis or vascularitis. Understanding the pathomechanisms involved could provide interesting clue for understanding not only the skin manifestations but also some of the other systemic symptoms associated to covid-19 infection. This study plan to characterize these acral manifestations by analyzing the clinical and dermoscopic patterns and to correlate them with the non-invasive vascular explorations but also immune and coagulopathy explorations that are done in the CHU of Nice in covid-19 patients.
Study Type
OBSERVATIONAL
Enrollment
30
CHU de Nice
Nice, France
RECRUITINGClinical skin manifestations
Type and description of the skin manifestations with a special focus on patients with chilblains
Time frame: 3 months
Histology and biological data
Data on Histology (HE staining and immunofluorescence) and on biology (blood cells counts, CRP and immune profile) will be collected in covid patient with skin manifestation
Time frame: 3 months
Non invasive vascular examination
Vascular examination will be performed by Capillaroscopy, laser-doppler or lung TDM if clinically required
Time frame: 3 months
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