Investigator is studying the effects of Lidocaine and Adrenaline Soaked Gauze vs Normal Saline Soaked Gauze at Skin Graft Donor Site of Thigh. Haemostatic effect, epithelization and post operative pain will be assessed on follow up.
After admission participants will be randomized either to be in Group A or Group B. Closed envelop technique will be used for random assignment of the patients. Group A will be receiving 2% lidocaine and 1:100,000 adrenaline soaked gauze while group B will be given only normal saline soaked gauze at donor-site for ten minutes. The primary end point of study is intraoperative bleeding. The secondary end points of study include no. of dressings required in first 24 hours after surgery, donor site epithelization at 14th post-operative day, post-operative pain in first 24 hours after surgery along with systemic analgesia requirement after surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
60
Topical application of 2% Lidocaine and 1:100,000 Adrenaline in the form of dressing will be applied over skin graft donor site of thigh for 10 minutes.
Topical application of Normal saline will be applied over skin graft donor site of thigh as a control group.
Zaara Zahid
Karachi, Sindh, Pakistan
Intra operatieve bleeding
Intra-operative Bleeding from donor site of graft will be assessed per operatively as being normal or more than normal.
Time frame: per operative
Post operative bleeding
post operative bleeding will be assesd in post operative period by number of dressings required.
Time frame: 24 hours
Post operative pain
post operative pain will be assessed in the post operative period by visual analog score. Score ranges from 0 to 10 with 0 indicating no pain whereas 10 is worst pain.
Time frame: 24 hours
Analgesia requirement
Post operative analgesia requirement of patient will be observed by number of medications required
Time frame: 24 hours
Epithelization of donor site
Epithelization over donor site will be assessed on 14th post operative day by subjective assesment
Time frame: 14 days
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