Photoscreening for Retinoblastoma

Phoenix Children's Hospital

Overview

Retinoblastoma is the most common pediatric eye malignancy and manifests between 1 and 5 years of age. The tumor is most often diagnosed by leukocoria ( white reflex in the pupil). There is often a significant delay in diagnosis and early diagnosis enables good life prognosis and better vision outcome.There is currently not a standardized screening protocol for detection of retinoblastoma. Vision screening methods are recommended for children 3-5 years of age. The investigators are attempting to use instrument based screening started from birth to detect leukocoria.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Conditions

Retinoblastoma

Interventions

Photoscreening -DEVICE

external picture taken with a an phone based app

Eligibility

Sex: ALLMin age: 0 YearsMax age: 10 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age birth to 10 years * Informed consent given by parent or legal guardian Exclusion Criteria: * None

Outcomes

Primary Outcomes

Reliability to detect leukocoria

Testing the reliability of the app to detect leukocoria with good sensitivity and specificity

Time frame: 1 year

Data from ClinicalTrials.gov

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